Cadherin-16 Antikörper (AA 700-829)

Produktnummer ABIN8120100

Der Maus Monoklonal anti-Cadherin-16 Antikörper wird verwendet zum Nachweis von Cadherin-16 in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Cadherin-16 Antikörper (AA 700-829) (ABIN8120100)

Target: Cadherin-16 (CDH16)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cadherin-16 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: AB1739

Produktdetails anti-Cadherin-16 Antikörper

Bindungsspezifität: AA 700-829

Verwendungszweck: KSP-Cadherin mouse mAb

Spezifität: The antibody can specifically recognize human KSP-Cadherin protein, and has no cross reaction with E-cadherin, N-cadherin, P-cadherin.

Aufreinigung: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogen: A synthetic peptide corresponding to the amino acid region 700 - 829 of the human KSP - Cadherin protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC, 1:200-1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu Cadherin-16

Target: Cadherin-16 (CDH16)

Andere Bezeichnung: KSP-Cadherin

Hintergrund:

Synonyms: CAD16_HUMAN, Cadherin 16, Cadherin 16 KSP cadherin, Cadherin kidney, Cadherin-16, CDH 16, CDH16, Kidney cadherin, Kidney specific cadherin, Kidney-specific cadherin, Ksp cadherin, Ksp-cadherin, PRO1340, UNQ695

Background: KSP-cadherin, also known as cadherin-16, is a new member of the calcium adhesion molecule family and plays an important role during embryonic development. It was specifically expressed in kidney, only in renal tubular epithelium, basement membrane and collecting duct epithelium, but not in glomerulus, renal interstitial cells and blood vessels. The loss of these adhesion molecules in renal cell tumors may be related to tumor dedifferentiation and lymph node metastasis. KSP-cadherin has a sensitivity of up to 100 % in renal chromophobe cell carcinoma and 95 % in renal eosinophilic adenoma.

Gene Name: CDH16

Protein Name: KSP-Cadherin

Gen-ID: 1014

UniProt: O75309