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Cadherin-16 Antikörper (AA 371-507)

CDH16 Reaktivität: Human WB, ELISA, IHC (f), Coat Wirt: Maus Monoclonal CDH16-2125 unconjugated
Produktnummer ABIN6939022
  • Target Alle Cadherin-16 (CDH16) Antikörper anzeigen
    Cadherin-16 (CDH16)
    Bindungsspezifität
    • 8
    • 8
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 371-507
    Reaktivität
    • 88
    • 40
    • 31
    • 22
    • 21
    • 1
    • 1
    • 1
    Human
    Wirt
    • 55
    • 34
    • 1
    Maus
    Klonalität
    • 48
    • 42
    Monoklonal
    Konjugat
    • 51
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Cadherin-16 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 39
    • 39
    • 36
    • 24
    • 19
    • 14
    • 6
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Coating (Coat)
    Spezifität
    This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
    Kreuzreaktivität (Details)
    Human,
    Aufreinigung
    200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
    Immunogen
    Recombinant fragment (around aa 371-507) of human CDH16 protein (exact sequence is proprietary)
    Klon
    CDH16-2125
    Isotyp
    IgG1
    Top Product
    Discover our top product CDH16 Primärantikörper
  • Applikationshinweise

    Positive Control: Normal kidney or renal cell carcinoma.

    Known Application: ELISA (For coating, order Ab without BSA),Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
    Haltbarkeit
    24 months
  • Target
    Cadherin-16 (CDH16)
    Andere Bezeichnung
    CDH16 (CDH16 Produkte)
    Synonyme
    cadherin 16 antikoerper, CDH16 antikoerper, Cdh16 antikoerper
    Hintergrund
    Cadherin-16 (CDH16), Kidney-specific cadherin, Ksp-cadherin antibody,Ksp-Cadherin / CDH16 (Renal Cell Marker)
    Cellular localisation: Cell Surface and Cytoplasmic
    Molekulargewicht
    130kDa
    Gen-ID
    1014, 513660
    UniProt
    O75309
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