Cadherin-16 Antikörper (AA 700-829)

Produktnummer ABIN8120099

Dieser Maus Monoklonal Antikörper detektiert spezifisch Cadherin-16 in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Cadherin-16 Antikörper (AA 700-829) (ABIN8120099)

Target: Cadherin-16 (CDH16)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cadherin-16 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: AB1739

Produktdetails anti-Cadherin-16 Antikörper

Bindungsspezifität: AA 700-829

Verwendungszweck: KSP-Cadherin Mouse mAb (Ready to Use)

Spezifität: The antibody can specifically recognize human KSP- Cadherin protein, and has no cross reaction with E- cadherin, N- cadherin, P- cadherin.

Aufreinigung: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 700 - 829 of the human KSP - Cadherin protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: It has been optimized for direct use, requiring no further dilution.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C. Avoid freeze.

Details zu Cadherin-16

Target: Cadherin-16 (CDH16)

Andere Bezeichnung: KSP-Cadherin

Hintergrund:

Synonyms: CAD16_HUMAN, Cadherin 16, Cadherin 16 KSP cadherin, Cadherin kidney, Cadherin-16, CDH 16, CDH16, Kidney cadherin, Kidney specific cadherin, Kidney-specific cadherin, Ksp cadherin, Ksp-cadherin, PRO1340, UNQ695

Background: KSP- cadherin, also known as cadherin- 16, is a new member of the calcium adhesion molecule family and plays an important role during embryonic development. It was specifically expressed in kidney, only in renal tubular epithelium, basement membrane and collecting duct epithelium, but not in glomerulus, renal interstitial cells and blood vessels. The loss of these adhesion molecules in renal cell tumors may be related to tumor dedifferentiation and lymph node metastasis. KSP- cadherin has a sensitivity of up to 100 % in renal chromophobe cell carcinoma and 95 % in renal eosinophilic adenoma.

Gene Name: CDH16

Protein Name: KSP-Cadherin

Gen-ID: 1014

UniProt: O75309