BTK Antikörper (pSer180)
Kurzübersicht für BTK Antikörper (pSer180) (ABIN8120046)
Target
Alle BTK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer180
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Verwendungszweck
- Btk (Phospho Ser180) Antibody
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Spezifität
- This antibody detects endogenous levels of Human Btk (phospho-Ser180)
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Aufreinigung
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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Immunogen
- Synthesized phosho peptide around human Btk (Ser180)
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Isotyp
- IgG
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Applikationshinweise
- WB 1:1000-2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
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Andere Bezeichnung
- Btk
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Hintergrund
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Synonyms: Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinaemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)
Background: The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013],
Gene Name: BTK AGMX1 ATK BPK
Protein Name: Btk (Ser180)
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Gen-ID
- 695
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UniProt
- Q06187
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling
Target
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