BMI1 Antikörper

Produktnummer ABIN8120003

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch BMI1 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für BMI1 Antikörper (ABIN8120003)

Target: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BMI1 Antikörper

Verwendungszweck: Bmi-1 Antibody(F270)

Spezifität: This antibody detects endogenous levels of human Bmi-1

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Recombinant Protein derived from human Bmi-1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu BMI1

Target: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Andere Bezeichnung: Bmi-1

Hintergrund:

Synonyms: Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)

Background: BMI1 proto-oncogene, polycomb ring finger(BMI1) Homo sapiens This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015],

Gene Name: BMI1 PCGF4 RNF51

Protein Name: Bmi-1

Gen-ID: 100532731

UniProt: P35226

Pathways: Zellzyklus, Autophagie