BBS7 Antikörper (AA 85-135)

Produktnummer ABIN8119957

Der Kaninchen Polyklonal anti-BBS7 Antikörper (ABIN8119957) detektiert spezifisch BBS7 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für BBS7 Antikörper (AA 85-135) (ABIN8119957)

Target: BBS7 (Bardet-Biedl Syndrome 7 (BBS7))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BBS7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BBS7 Antikörper

Bindungsspezifität: AA 85-135

Verwendungszweck: BBS7 Antibody

Spezifität: This antibody detects endogenous levels of BBS7 at Human/Mouse

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human BBS7 AA range: 85-135

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu BBS7

Target: BBS7 (Bardet-Biedl Syndrome 7 (BBS7))

Andere Bezeichnung: BBS7

Hintergrund:

Background: This gene encodes one of eight proteins that form the BBSome complex containing BBS1, BBS2, BBS4, BBS5, BBS7, BBS8, BBS9 and BBIP10. The BBSome complex is believed to recruit Rab8(GTP) to the primary cilium and promote ciliogenesis. The BBSome complex assembly is mediated by a complex composed of three chaperonin-like BBS proteins (BBS6, BBS10, and BBS12) and CCT/TRiC family chaperonins. Mutations in this gene are implicated in Bardet-Biedl syndrome, a genetic disorder whose symptoms include obesity, retinal degeneration, polydactyly and nephropathy, however, mutations in this gene and the BBS8 gene are thought to play a minor role and mutations in chaperonin-like BBS genes are found to be a major contributor to disease development in a multiethnic Bardet-Biedl syndrome patient population. Two transcript variants encoding distinct isoforms have been identified for this gene.[provided by RefSeq, Oct 2014],

Gene Name: BBS7 BBS2L1

Protein Name: BBS7

Gen-ID: 55212

UniProt: Q8IWZ6

Pathways: Hedgehog Signalweg