BBS7 Antikörper (AA 1-270)

Produktnummer ABIN7265825

Produktdetails anti-BBS7 Antikörper

Target: BBS7 (Bardet-Biedl Syndrome 7 (BBS7))

Bindungsspezifität: AA 1-270

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BBS7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Verwendungszweck: BBS7 Rabbit pAb

Sequenz: MDLILNRMDY LQVGVTSQKT MKLIPASRHR ATQKVVIGDH DGVVMCFGMK KGEAAAVFKT LPGPKIARLE LGGVINTPQE KIFIAAASEI RGFTKRGKQF LSFETNLTES IKAMHISGSD LFLSASYIYN HYCDCKDQHY YLSGDKINDV ICLPVERLSR ITPVLACQDR VLRVLQGSDV MYAVEVPGPP TVLALHNGNG GDSGEDLLFG TSDGKLALIQ ITTSKPVRKW EIQNEKKRGG ILCIDSFDIV GDGVKDLLVG RDDGMVEVYS

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human BBS7 (NP_060660.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu BBS7

Target: BBS7 (Bardet-Biedl Syndrome 7 (BBS7))

Andere Bezeichnung: BBS7 (BBS7 Produkte)

Synonyme: BBS7 antikoerper, bbs2l1 antikoerper, BBS2L1 antikoerper, id:ibd5048 antikoerper, zgc:153772 antikoerper, 8430406N16Rik antikoerper, Bardet-Biedl syndrome 7 antikoerper, bardet-biedl syndrome 7 antikoerper, Bardet-Biedl syndrome 7 L homeolog antikoerper, Bardet-Biedl syndrome 7 (human) antikoerper, BBS7 antikoerper, bbs7 antikoerper, MICPUN_100192 antikoerper, MICPUCDRAFT_16331 antikoerper, bbs7.L antikoerper, Bbs7 antikoerper

Hintergrund: This gene encodes one of eight proteins that form the BBSome complex containing BBS1, BBS2, BBS4, BBS5, BBS7, BBS8, BBS9 and BBIP10. The BBSome complex is believed to recruit Rab8(GTP) to the primary cilium and promote ciliogenesis. The BBSome complex assembly is mediated by a complex composed of three chaperonin-like BBS proteins (BBS6, BBS10, and BBS12) and CCT/TRiC family chaperonins. Mutations in this gene are implicated in Bardet-Biedl syndrome, a genetic disorder whose symptoms include obesity, retinal degeneration, polydactyly and nephropathy, however, mutations in this gene and the BBS8 gene are thought to play a minor role and mutations in chaperonin-like BBS genes are found to be a major contributor to disease development in a multiethnic Bardet-Biedl syndrome patient population. Two transcript variants encoding distinct isoforms have been identified for this gene.[provided by RefSeq, Oct 2014],BBS2L1,BBS7,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Endocrine & Metabolism,Neuroscience,BBS7

Molekulargewicht: 75kDa/80kDa

Gen-ID: 55212

UniProt: Q8IWZ6

Pathways: Hedgehog Signalweg