LIN28B Antikörper (C-Term)

Produktnummer ABIN8104468

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch LIN28B in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Schaf, Hund, Meerschweinchen und Kaninchen.

Kurzübersicht für LIN28B Antikörper (C-Term) (ABIN8104468)

Target: LIN28B (Lin-28 Homolog B (LIN28B))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Schaf, Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIN28B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LIN28B Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: LIN28B Antibody - C-terminal region

Sequenz: GCTSPPFPQE ARAEISERSG RSPQEASSTK SSIAPEEQSK KGPSVQKRKK

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 100%, Rabbit: 86%, Rat: 93%, Sheep: 100%

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human LN28B

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50332-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu LIN28B

Target: LIN28B (Lin-28 Homolog B (LIN28B))

Andere Bezeichnung: LIN28B

Hintergrund:

Background Information: The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation.

Gene Name: lin-28 homolog B

Alternative Symbols: CSDD2

Protein Name: protein lin-28 homolog B

Molekulargewicht: 27kDa

Gen-ID: 389421

NCBI Accession: NP_001004317

UniProt: Q6ZN17