COL3 Antikörper

Produktnummer ABIN8065429

Der Maus Monoklonal anti-COL3 Antikörper (Klon 1E7-D7-Col3) (ABIN8065429) detektiert spezifisch COL3 in WB, IHC und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für COL3 Antikörper (ABIN8065429)

Target: COL3 (Collagen, Type III (COL3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser COL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Güteklasse: Carrier-free

Klon: 1E7-D7-Col3

Produktdetails anti-COL3 Antikörper

Verwendungszweck: Anti-Type III Collagen Antibody

Spezifität: CSI 007-01 is highly specific for type III collagen. It has been shown to have no cross-ractivity with type I and V collagens by ELISA and immunoblotting. There is no evidence for cross-reactivity with other connective tissue proteins (laminin, fibronectin, elastin). Epitope is located approximately 100nm from the N-terminal of the molecule.

Homologie: Canine,Human,Kangaroo,and Rat

Aufreinigung: Protein A or Protein G purified

Immunogen: Acid-digested pepsin soluble human type III collagen

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C without exposure to light

Haltbarkeit: 24 months

Details zu COL3

Target: COL3 (Collagen, Type III (COL3))

Andere Bezeichnung: Type III Collagen

Hintergrund: COL3A1, EDS4A, EDSVASC, PMGEDSV, collagen alpha-1(III) chain, Ehlers-Danlos syndrome type IV, autosomal dominant, alpha-1 type III collagen, alpha1 (III) collagen, collagen, fetal, collagen, type III, alpha 1,Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12.,COL3A1,Type III collagen is present in the walls of arteries, intestines and the uterus, where it strenghtens the connective tissue. Patients with defects in the type III collagen (ex. Ehlers-Danlos syndrome) are at risk of rupture of major arteries or the intestine.

Molekulargewicht: 139 kDa

Gen-ID: 1281

UniProt: P02461