COL3 Antikörper

Produktnummer ABIN135050

Es sind 29+ Publikationen für dieses Produkt verfügbar. Der Ziege Polyklonal anti-COL3 Antikörper wird verwendet zum Nachweis von COL3 in Proben von Human, Ratte, Maus, Kaninchen, Hund, Huhn, Rind (Kuh), Chinchilla chinchilla, Meerschweinchen, Hamster, Pferd, Schwein, Rhesusaffen und Tree shrew. Er wurde validiert für WB, ELISA, IHC (fro), ICC, IHC (p), FACS und IEM.

Kurzübersicht für COL3 Antikörper (ABIN135050)

Target: COL3 (Collagen, Type III (COL3))

Reaktivität: Human, Ratte, Maus, Kaninchen, Hund, Huhn, Rind (Kuh), Chinchilla chinchilla, Meerschweinchen, Hamster, Pferd, Schwein, Rhesusaffen, Tree shrew

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser COL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunoelectron Microscopy (IEM)

Produktdetails anti-COL3 Antikörper

Verwendungszweck: Goat Anti-Type III Collagen-UNLB

Spezifität: Reacts with conformational determinants on type III collagen Referenced species reactivities include - Human 2,5,11,12,32,33,35-37 Chicken 22,23 Hamster 18,24 Mouse 4,6,13,15,34,39 Chinchilla 26 Porcine 1,5,17,29 Rat 5,10,14,20,31 Equine 25 Rabbit 9,16,19,21,38 Bovine 8,27 Feline 30 Rhesus 7 Canine 3,5 Guinea Pig 21 Tree Shrew 28

Kreuzreaktivität (Details): Exhibits < 10 % cross reactivity with collagen type II, III, IV, V and VI. The antibody has not been tested for reactivity with other ECM proteins (e.g., laminin, fibronectin).

Produktmerkmale: Purified Anti-Type III Collagen antibody for use in ELISA, immunohistochemistry / immunocytochemistry, electron microscopy, flow cytometry, and western blotting assays.

Aufreinigung: Purified by affinity chromatography on type III collagen covalently linked to agarose, cross-adsorbed against Collagen types I, II, IV, V, and VI for minimal reactivity

Immunogen: Type III collagen

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Pooled antisera from goats hyperimmunized with type III collagen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.4 mg/mL

Buffer: Borate buffered saline, pH 8.2

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C

Referenzen für anti-COL3 Antikörper (ABIN135050)

Fernandes, Reilly, Schrock, Hocking, Oakes, Fowell: "CD4+ T Cell Interstitial Migration Controlled by Fibronectin in the Inflamed Skin." in: Frontiers in immunology, Vol. 11, pp. 1501, (2020) (PubMed).

Sembach, Fink, Johansen, Boland, Secher, Thrane, Nielsen, Fosgerau, Vrang, Jelsing, Pedersen, Østergaard: "Impact of sex on diabetic nephropathy and the renal transcriptome in UNx db/db C57BLKS mice." in: Physiological reports, Vol. 7, Issue 24, pp. e14333, (2020) (PubMed).

Becker, OConnell, Vo, Cain, Tampe, Bizarro, Sugimoto, McGow, Asara, Lovisa, McAndrews, Zielinski, Lorenzi, Zeisberg, Raza, LeBleu, Kalluri: "Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer." in: Cell reports, Vol. 31, Issue 9, pp. 107701, (2020) (PubMed).

Buhl, Djudjaj, Klinkhammer, Ermert, Puelles, Lindenmeyer, Cohen, He, Borkham-Kamphorst, Weiskirchen, Denecke, Trairatphisan, Saez-Rodriguez, Huber, Olson, Floege, Boor: "Dysregulated mesenchymal PDGFR-β drives kidney fibrosis." in: EMBO molecular medicine, Vol. 12, Issue 3, pp. e11021, (2020) (PubMed).

Dobie, Wilson-Kanamori, Henderson, Smith, Matchett, Portman, Wallenborg, Picelli, Zagorska, Pendem, Hudson, Wu, Budas, Breckenridge, Harrison, Mole, Wigmore, Ramachandran, Ponting, Teichmann, Marioni et al.: "Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis. ..." in: Cell reports, Vol. 29, Issue 7, pp. 1832-1847.e8, (2020) (PubMed).

Welc, Flores, Wehling-Henricks, Ramos, Wang, Bertoni, Tidball: "Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy." in: Nature communications, Vol. 10, Issue 1, pp. 2788, (2019) (PubMed).

Delestre-Delacour, Carmon, Laguerre, Estay-Ahumada, Courel, Elias, Jeandel, Rayo, Peinado, Sengmanivong, Gasman, Coudrier, Anouar, Montero-Hadjadje: "Myosin 1b and F-actin are involved in the control of secretory granule biogenesis." in: Scientific reports, Vol. 7, Issue 1, pp. 5172, (2019) (PubMed).

He, Zhang, Tolosa, Goru, Chen, Misra, Robinson, Yuen: "A new, easily generated mouse model of diabetic kidney fibrosis." in: Scientific reports, Vol. 9, Issue 1, pp. 12549, (2019) (PubMed).

Ellenbroek, de Haan, van Klarenbosch, Brans, van de Weg, Smeets, de Jong, Arslan, Timmers, Goumans, Hoefer, Doevendans, Pasterkamp, Meyaard, de Jager: "Leukocyte-Associated Immunoglobulin-like Receptor-1 is regulated in human myocardial infarction but its absence does not affect infarct size in mice." in: Scientific reports, Vol. 7, Issue 1, pp. 18039, (2019) (PubMed).

Qiao, Dai, Nikolova, Jin, Li, Xiao, Li, Moy, Xiao: "Amelioration of Muscle and Nerve Pathology in LAMA2 Muscular Dystrophy by AAV9-Mini-Agrin." in: Molecular therapy. Methods & clinical development, Vol. 9, pp. 47-56, (2018) (PubMed).

Wada, Kawada, Hirai, Toda, Iwamoto, Hasegawa, Sakai: "Enhanced anastomotic healing by Daikenchuto (TJ-100) in rats." in: Scientific reports, Vol. 8, Issue 1, pp. 1091, (2018) (PubMed).

Westendorp, Büller, Karpus, van Dop, Koster, Versteeg, Koelink, Snel, Meisner, Roelofs, Uhmann, Ver Loren van Themaat, Heijmans, Hahn, Muncan, Wildenberg, van den Brink: "Indian Hedgehog Suppresses a Stromal Cell-Driven Intestinal Immune Response." in: Cellular and molecular gastroenterology and hepatology, Vol. 5, Issue 1, pp. 67-82.e1, (2018) (PubMed).

de Bruyn, Becker, Steenkamer, Wildenberg, Meijer, Buskens, Bemelman, Löwenberg, Ponsioen, van den Brink, DHaens: "Intestinal fibrosis is associated with lack of response to Infliximab therapy in Crohn's disease." in: PLoS ONE, Vol. 13, Issue 1, pp. e0190999, (2018) (PubMed).

Pu, Zhang, Huang, Tian, He, Wang, Zhang, Liu, Li, Li, Zhao, Liu, Lu, Zhou, Huang, Nie, Yan, Hui, Lui, Zhou: "Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration." in: Nature communications, Vol. 7, pp. 13369, (2018) (PubMed).

Poosti, Bansal, Yazdani, Prakash, Beljaars, van den Born, de Borst, van Goor, Hillebrands, Poelstra: "Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice." in: Oncotarget, Vol. 7, Issue 34, pp. 54240-54252, (2018) (PubMed).

Hijmans, Shrestha, Sarpong, Yazdani, El Masri, de Jong, Navis, Vivès, van den Born: "High sodium diet converts renal proteoglycans into pro-inflammatory mediators in rats." in: PLoS ONE, Vol. 12, Issue 6, pp. e0178940, (2017) (PubMed).

Hijmans, Rasmussen, Yazdani, Navis, van Goor, Karsdal, Genovese, van den Born: "Urinary collagen degradation products as early markers of progressive renal fibrosis." in: Journal of translational medicine, Vol. 15, Issue 1, pp. 63, (2017) (PubMed).

Poosti, Pham, Oosterhuis, Poelstra, van Goor, Olinga, Hillebrands: "Precision-cut kidney slices (PCKS) to study development of renal fibrosis and efficacy of drug targeting ex vivo." in: Disease models & mechanisms, Vol. 8, Issue 10, pp. 1227-36, (2016) (PubMed).

Yazdani, Hijmans, Poosti, Dam, Navis, van Goor, van den Born: "Targeting tubulointerstitial remodeling in proteinuric nephropathy in rats." in: Disease models & mechanisms, Vol. 8, Issue 8, pp. 919-30, (2016) (PubMed).

Abdul, Dixon, Walker, Horabin, Smith, Weir, Brewster, Deehan, Mann, Borthwick: "Fibrosis is a common outcome following total knee arthroplasty." in: Scientific reports, Vol. 5, pp. 16469, (2016) (PubMed).

Details zu COL3

Target: COL3 (Collagen, Type III (COL3))

Andere Bezeichnung: TypeIII Collagen

Hintergrund:

Description: Goat Anti-Type III Collagen-UNLB

NCBI_Official_Symbol: COL3A1

Synoynms: COL3

Gen-ID: 1281

UniProt: P02461