Bax Inhibitor 1 Antikörper (N-Term) (Fluoro488)

Produktnummer ABIN8048868

Der Kaninchen Polyklonal anti-Bax Inhibitor 1 Antikörper wird verwendet zum Nachweis von Bax Inhibitor 1 in Proben von Human. Er wurde validiert für FACS.

Kurzübersicht für Bax Inhibitor 1 Antikörper (N-Term) (Fluoro488) (ABIN8048868)

Target: Bax Inhibitor 1 (TMBIM6) (Transmembrane BAX Inhibitor Motif Containing 6 (TMBIM6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Bax Inhibitor 1 Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Bax Inhibitor 1 Antikörper (Fluoro488)

Bindungsspezifität: N-Term

Verwendungszweck: Anti-BI-1/TMBIM6 Antibody Fluoro488 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: identical to the related mouse,rat sequences.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human BI-1/TMBIM6, identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Bax Inhibitor 1

Target: Bax Inhibitor 1 (TMBIM6) (Transmembrane BAX Inhibitor Motif Containing 6 (TMBIM6))

Andere Bezeichnung: TMBIM6

Hintergrund:

Background: Bax inhibitor 1 is a protein that in humans is encoded by the TMBIM6 gene. Enables endoribonuclease inhibitor activity and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of RNA metabolic process, negative regulation of intrinsic apoptotic signaling pathway, and response to L-glutamate. Acts upstream of or within negative regulation of calcium ion transport into cytosol. Located in endoplasmic reticulum membrane and mitochondrial membrane. Biomarker of cervical squamous cell carcinoma and prostate carcinoma.

Gene Full Name: transmembrane BAX inhibitor motif containing 6

Gen-ID: 7009

UniProt: P55061

Pathways: Response to Water Deprivation, ER-Nucleus Signaling