Bax Inhibitor 1 Antikörper

Produktnummer ABIN7882547

Der Kaninchen Polyklonal anti-Bax Inhibitor 1 Antikörper (ABIN7882547) detektiert spezifisch Bax Inhibitor 1 in WB, IHC (p) und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Bax Inhibitor 1 Antikörper (ABIN7882547)

Target: Bax Inhibitor 1 (TMBIM6) (Transmembrane BAX Inhibitor Motif Containing 6 (TMBIM6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Bax Inhibitor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-Bax Inhibitor 1 Antikörper

Verwendungszweck: BI-1 Antibody / Bax inhibitor 1 / TMBIM6

Sequenz: RKINFDALLK FSHITPSTQQ HLK

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids RKINFDALLKFSHITPSTQQHLK were used as the immunogen for the BI-1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the BI-1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the BI-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Bax Inhibitor 1

Target: Bax Inhibitor 1 (TMBIM6) (Transmembrane BAX Inhibitor Motif Containing 6 (TMBIM6))

Andere Bezeichnung: BI-1

Hintergrund: Bax inhibitor 1 (BI-1) is a protein that in humans is encoded by the TMBIM6 gene. Enables endoribonuclease inhibitor activity and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of RNA metabolic process, negative regulation of intrinsic apoptotic signaling pathway, and response to L-glutamate. Acts upstream of or within negative regulation of calcium ion transport into cytosol. Located in endoplasmic reticulum membrane and mitochondrial membrane. Biomarker of cervical squamous cell carcinoma and prostate carcinoma.

UniProt: P55061

Pathways: Response to Water Deprivation, ER-Nucleus Signaling