TLR8 Antikörper (C-Term)

Produktnummer ABIN8047445

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TLR8 in WB. Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für TLR8 Antikörper (C-Term) (ABIN8047445)

Target: TLR8 (Toll-Like Receptor 8 (TLR8))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Güteklasse: Carrier-free

Produktdetails anti-TLR8 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Anti-Toll-like receptor 8 TLR8 Antibody

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: identical to the related mouse sequence.

Produktmerkmale: Anti-Toll-like receptor 8 TLR8 Antibody. Tested in WB applications. This antibody reacts with Human, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TLR8, identical to the related mouse sequence.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Rat

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TLR8

Target: TLR8 (Toll-Like Receptor 8 (TLR8))

Andere Bezeichnung: TLR8

Hintergrund:

Background: TLR8 (Toll-like receptor 8) is a protein that in humans is encoded by the TLR8 gene. TLR8 has also been designated as CD288 (cluster of differentiation 288).The TLR8 gene is mapped to Xp22.3-p22.2 by Chuang and Ulevitch (2000) and Du et al. (2000). The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. TLR8 recognises G-rich oligonucleotides.

Gene Full Name: toll like receptor 8

Sequence Similarities: Belongs to the Toll-like receptor family.

Molekulargewicht: 120 kDa

Gen-ID: 51311

UniProt: Q9NR97

Pathways: TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades