TARDBP Antikörper (AA 1-264) (Fluoro594)
Kurzübersicht für TARDBP Antikörper (AA 1-264) (Fluoro594) (ABIN8045402)
Target
Alle TARDBP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 1-264
-
Verwendungszweck
- Anti-TDP-43/TARDBP Antibody Fluoro594 Conjugated
-
Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
-
Aufreinigung
- Immunogen affinity purified.
-
Immunogen
- E.coli-derived human TDP-43/TARDBP recombinant protein (Position: M1-H264).
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
Haltbarkeit
- 12 months
-
-
- TARDBP (TAR DNA Binding Protein (TARDBP))
-
Andere Bezeichnung
- TARDBP
-
Hintergrund
-
Background: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Gene Full Name: TAR DNA binding protein
-
Gen-ID
- 23435
-
UniProt
- Q13148
-
Pathways
- Positive Regulation of Peptide Hormone Secretion
Target
-