TBK1 Antikörper (AA 1-729)
Kurzübersicht für TBK1 Antikörper (AA 1-729) (ABIN8045353)
Target
Alle TBK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Bindungsspezifität
- AA 1-729
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Verwendungszweck
- Anti-NAK/TBK1 Antibody
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
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Produktmerkmale
- Anti-NAK/TBK1 Antibody. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human NAK/TBK1 recombinant protein (Position: M1-L729).
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Isotyp
- IgG
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Applikationshinweise
- Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse ELISA, 0.1-0.5 μg/mL, -
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Konzentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Haltbarkeit
- 12 months
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- TBK1 (TANK-Binding Kinase 1 (TBK1))
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Andere Bezeichnung
- TBK1
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Hintergrund
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Background: Serine/threonine-protein kinase TBK1, also called TANK-binding kinase 1 or NF-kappa-B-activating kinase is an enzyme that in humans is encoded by the TBK1 gene. The gene was assigned to human chromosome 12q14.2. Serine/threonine kinase plays an essential role in regulating inflammatory responses to foreign agents. TBK1 and NF-kappa-B signaling are essential in KRAS mutant tumors, and established a general approach for the rational identification of codependent pathways in cancer.
Gene Full Name: TANK binding kinase 1
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Molekulargewicht
- 84 kDa
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Gen-ID
- 29110
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UniProt
- Q9UHD2
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Pathways
- TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interaktom
Target
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