SMAD3 Antikörper (Middle Region) (APC)
Kurzübersicht für SMAD3 Antikörper (Middle Region) (APC) (ABIN8038176)
Target
Alle SMAD3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- Anti-Smad3 Antibody APC Conjugated
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Spezifität
- No cross reactivity with other proteins.
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
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Homologie
- identical to the related mouse,rat sequences.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- A synthetic peptide corresponding to a sequence in the middle region of human Smad3, identical to the related mouse and rat sequences.
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Isotyp
- IgG
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Applikationshinweise
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
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Kommentare
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Applications are recommended based on the unconjugated antibody.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Haltbarkeit
- 12 months
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- SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))
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Andere Bezeichnung
- SMAD3
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Hintergrund
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Background: Mothers against decapentaplegic homolog 3 also known as SMAD family member 3 or SMAD3 is a protein that in humans is encoded by the SMAD3 gene. SMAD3 is a member of the SMAD family of proteins. It is located in 15q22.33. And it mediates the signals from the transforming growth factor beta (TGF-β) super family ligands that regulate cell proliferation, differentiation and death. Based on its essential role in TGF beta signaling pathway, SMAD3 has been related with tumor growth in cancer development.
Gene Full Name: SMAD family member 3
Sequence Similarities: Belongs to the dwarfin/SMAD family.
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Gen-ID
- 4088
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UniProt
- P84022
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Pathways
- Zellzyklus, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagie
Target
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