SETDB2 Antikörper (AA 20-714) (Biotin)

Produktnummer ABIN8036766

Der Kaninchen Polyklonal anti-SETDB2 Antikörper wird verwendet zum Nachweis von SETDB2 in Proben von Ratte und Maus. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für SETDB2 Antikörper (AA 20-714) (Biotin) (ABIN8036766)

Target: SETDB2 (SET Domain, Bifurcated 2 (SETDB2))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SETDB2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-SETDB2 Antikörper (Biotin)

Bindungsspezifität: AA 20-714

Verwendungszweck: Anti-CLLD8/Setdb2 Antibody Biotin Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived rat CLLD8/Setdb2 recombinant protein (Position: K20-I714).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SETDB2

Target: SETDB2 (SET Domain, Bifurcated 2 (SETDB2))

Andere Bezeichnung: Setdb2

Hintergrund:

Background: SET domain bifurcated histone lysine methyltransferase 2 is a protein in humans encoded by the SETDB2 gene. It is mapped to 13q14.2. This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants.

Gene Full Name: SET domain bifurcated histone lysine methyltransferase 2

Gen-ID: 100361710

UniProt: M0RA29