Serotonin Receptor 2B Antikörper (C-Term)
Kurzübersicht für Serotonin Receptor 2B Antikörper (C-Term) (ABIN8036236)
Target
Alle Serotonin Receptor 2B (HTR2B) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Bindungsspezifität
- C-Term
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Verwendungszweck
- Anti-5HT2B Receptor/HTR2B Antibody
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Spezifität
- No cross reactivity with other proteins.
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
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Homologie
- different from the related mouse sequence by six amino acids,and from the related rat sequence by nine amino acids.
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Produktmerkmale
- Anti-5HT2B Receptor/HTR2B Antibody. Tested in WB applications. This antibody reacts with Human, Rat.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human 5HT2B Receptor, different from the related mouse sequence by six amino acids, and from the related rat sequence by nine amino acids.
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Isotyp
- IgG
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Applikationshinweise
- Western blot, 0.1-0.5 μg/mL, Human, Rat
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Konzentration
- 500 μg/mL
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Buffer
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Haltbarkeit
- 12 months
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- Serotonin Receptor 2B (HTR2B)
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Andere Bezeichnung
- HTR2B
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Hintergrund
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Background: 5HT2B Receptor is known as HTR2B. This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved.
Gene Full Name: 5-hydroxytryptamine receptor 2B
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.
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Molekulargewicht
- 54 kDa
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Gen-ID
- 3357
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UniProt
- P41595
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Pathways
- JAK-STAT Signalweg, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process
Target
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