Serotonin Receptor 2B Antikörper (N-Term)
Kurzübersicht für Serotonin Receptor 2B Antikörper (N-Term) (ABIN2779377)
Target
Alle Serotonin Receptor 2B (HTR2B) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Verwendungszweck
- HTR2B Antibody - N-terminal region
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Sequenz
- QTESIPEEMK QIVEEQGNKL HWAALLILMV IIPTIGGNTL VILAVSLEKK
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Homologie
- Cow: 100%, Dog: 80%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Pig: 87%
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Produktmerkmale
- This is a rabbit polyclonal antibody against HTR2B. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human HTR2B
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30716-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Serotonin Receptor 2B (HTR2B)
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Andere Bezeichnung
- HTR2B
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Hintergrund
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Background Information: Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets, central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.
Gene Name: 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
Alternative Symbols: 5-HT2B, 5-HT-2B, 5-HT(2B)
Protein Name: 5-hydroxytryptamine receptor 2B
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Molekulargewicht
- 54 kDa
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Gen-ID
- 3357
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NCBI Accession
- NP_000858
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UniProt
- P41595
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Pathways
- JAK-STAT Signalweg, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process
Target
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