Serotonin Receptor 2B Antikörper (N-Term)

Produktnummer ABIN2779377

Produktdetails anti-Serotonin Receptor 2B Antikörper

Target: Serotonin Receptor 2B (HTR2B)

Bindungsspezifität: N-Term

Reaktivität: Human, Rind (Kuh), Hund, Meerschweinchen, Schwein, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Serotonin Receptor 2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: QTESIPEEMK QIVEEQGNKL HWAALLILMV IIPTIGGNTL VILAVSLEKK

Homologie: Cow: 100%, Dog: 80%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Pig: 87%

Produktmerkmale: This is a rabbit polyclonal antibody against HTR2B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HTR2B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 481 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Serotonin Receptor 2B

Target: Serotonin Receptor 2B (HTR2B)

Andere Bezeichnung: HTR2B (HTR2B Produkte)

Synonyme: 5-HT2B antikoerper, 5HT2B antikoerper, 5htr2b antikoerper, HTR2B antikoerper, 5ht2b antikoerper, zgc:194094 antikoerper, zgc:194119 antikoerper, AJ012488 antikoerper, AV377389 antikoerper, 5-HT(2B) antikoerper, 5-hydroxytryptamine receptor 2B antikoerper, 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled antikoerper, 5-hydroxytryptamine (serotonin) receptor 2B antikoerper, HTR2B antikoerper, htr2b antikoerper, Htr2b antikoerper

Hintergrund: Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets, central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.
Alias Symbols: 5-HT(2B), 5-HT2B
Protein Interaction Partner: AGTR1, SNTA1, LNX1, GNAQ, GNA11,
Protein Size: 481

Molekulargewicht: 54 kDa

Gen-ID: 3357

NCBI Accession: NM_000867, NP_000858

UniProt: P41595

Pathways: JAK-STAT Signalweg, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process