SLFN11 Antikörper (AA 114-794) (Fluoro594)

Produktnummer ABIN8034739

Der Fluoro594-konjugierte Kaninchen Polyklonal anti-SLFN11 Antikörper (ABIN8034739) detektiert spezifisch SLFN11 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für SLFN11 Antikörper (AA 114-794) (Fluoro594) (ABIN8034739)

Target: SLFN11 (Schlafen Family Member 11 (SLFN11))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLFN11 Antikörper ist konjugiert mit Fluoro594

Applikation: Flow Cytometry (FACS)

Produktdetails anti-SLFN11 Antikörper (Fluoro594)

Bindungsspezifität: AA 114-794

Verwendungszweck: Anti-SLFN11 Antibody Fluoro594 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SLFN11 recombinant protein (Position: P114-D794).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu SLFN11

Target: SLFN11 (Schlafen Family Member 11 (SLFN11))

Andere Bezeichnung: SLFN11

Hintergrund:

Background: Schlafen family member 11 is a protein that in humans is encoded by the SLFN11 gene. SLFN11 is a nuclear protein that belongs to the Schlafen (SLFN) family of genes involved in cell cycle regulation and growth inhibition. Expression of SLFN11 predicts sensitivity of cancer cell lines to DNA-damaging agents. Evidence suggests that in the presence of DNA-targeted therapies, SLFN11 is recruited to stressed replication forks where it blocks replication leading to cell death. SLFN11 is being explored as a predictive biomarker for response to DNA-targeted therapies.

Gene Full Name: schlafen family member 11

Gen-ID: 91607

UniProt: Q7Z7L1