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SLFN11 Antikörper (AA 670-821) (Biotin)

SLFN11 Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN7168623
  • Target Alle SLFN11 Produkte
    SLFN11 (Schlafen Family Member 11 (SLFN11))
    Bindungsspezifität
    AA 670-821
    Reaktivität
    • 6
    • 1
    Human
    Wirt
    • 6
    Kaninchen
    Klonalität
    • 5
    • 1
    Polyklonal
    Konjugat
    • 3
    • 2
    • 1
    Dieser SLFN11 Antikörper ist konjugiert mit Biotin
    Applikation
    • 4
    • 3
    • 2
    • 1
    • 1
    ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human Schlafen family member 11 protein (670-821AA)
    Isotyp
    IgG
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SLFN11 (Schlafen Family Member 11 (SLFN11))
    Andere Bezeichnung
    SLFN11 (SLFN11 Produkte)
    Synonyme
    SLFN8/9 antikoerper, schlafen family member 11 antikoerper, SLFN11 antikoerper, LOC100071612 antikoerper
    Hintergrund

    Background: Interferon (IFN)-induced antiviral protein which acts as an inhibitor of retrovirus protein synthesis. Specifically abrogates the production of retroviruses such as human immunodeficiency virus 1 (HIV-1) by acting as a specific inhibitor of the synthesis of retroviruses encoded proteins in a codon-usage-dependent manner. Binds to tRNAs and exploits the unique viral codon bias towards A/T nucleotides. The exact inhibition mechanism is unclear: may either sequesters tRNAs, prevents their maturation via post-transcriptional processing or accelerates their deacylation. Does not inhibit reverse transcription, integration or production and nuclear export of viral RNA. May play a role in cell cycle arrest and/or induction of apoptosis in response to exogenously induced DNA damage.

    Aliases: SLFN11 antibody, Schlafen family member 11 antibody, EC 3.6.-.- antibody

    UniProt
    Q7Z7L1
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