RYK Antikörper (AA 66-607) (Fluoro550)

Produktnummer ABIN8034198

Der Kaninchen Polyklonal anti-RYK Antikörper wird verwendet zum Nachweis von RYK in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für RYK Antikörper (AA 66-607) (Fluoro550) (ABIN8034198)

Target: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RYK Antikörper ist konjugiert mit Fluoro550

Applikation: Flow Cytometry (FACS)

Produktdetails anti-RYK Antikörper (Fluoro550)

Bindungsspezifität: AA 66-607

Verwendungszweck: Anti-RYK Antibody Fluoro550 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human RYK shares 97.2% amino acid (aa) sequence identity with mouse RYK.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human RYK recombinant protein (Position: L66-V607). Human RYK shares 97.2% amino acid (aa) sequence identity with mouse RYK.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu RYK

Target: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Andere Bezeichnung: RYK

Hintergrund:

Background: The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene Full Name: receptor like tyrosine kinase

Gen-ID: 6259

UniProt: P34925

Pathways: RTK Signalweg, WNT Signalweg, Regulation of Cell Size