Poliovirus Receptor Antikörper (AA 28-331) (FITC)

Produktnummer ABIN8023672

Der FITC-konjugierte Maus Monoklonal anti-Poliovirus Receptor Antikörper (Klon 3B11E9) (ABIN8023672) detektiert spezifisch Poliovirus Receptor in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für Poliovirus Receptor Antikörper (AA 28-331) (FITC) (ABIN8023672)

Target: Poliovirus Receptor (PVR)

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Poliovirus Receptor Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Klon: 3B11E9

Produktdetails anti-Poliovirus Receptor Antikörper (FITC)

Bindungsspezifität: AA 28-331

Verwendungszweck: Anti-Poliovirus Receptor/PVR Antibody (monoclonal, 3B11E9) FITC Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Poliovirus Receptor/PVR recombinant protein (Position: D28-E331).

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Poliovirus Receptor

Target: Poliovirus Receptor (PVR)

Andere Bezeichnung: PVR

Hintergrund:

Background: CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that in humans is encoded by the PVR gene. The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: PVR cell adhesion molecule

Gen-ID: 5817

UniProt: P15151

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interaktom