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Poliovirus Receptor Antikörper (C-Term)

PVR Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB41981 unconjugated
Produktnummer ABIN1881709
  • Target Alle Poliovirus Receptor (PVR) Antikörper anzeigen
    Poliovirus Receptor (PVR)
    Bindungsspezifität
    • 13
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 314-342, C-Term
    Reaktivität
    • 54
    • 14
    • 4
    • 1
    Human
    Wirt
    • 43
    • 12
    • 9
    Kaninchen
    Klonalität
    • 40
    • 23
    • 1
    Polyklonal
    Konjugat
    • 33
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Poliovirus Receptor Antikörper ist unkonjugiert
    Applikation
    • 35
    • 24
    • 19
    • 11
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PVR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-342 amino acids from the C-terminal region of human PVR.
    Klon
    RB41981
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product PVR Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Nakai, Maniwa, Tanaka, Nishio, Yoshimura, Okita, Ohbayashi, Satoh, Ogita, Takai, Hayashi: "Overexpression of Necl-5 correlates with unfavorable prognosis in patients with lung adenocarcinoma." in: Cancer science, Vol. 101, Issue 5, pp. 1326-30, (2010) (PubMed).

    Carlsten, Norell, Bryceson, Poschke, Schedvins, Ljunggren, Kiessling, Malmberg: "Primary human tumor cells expressing CD155 impair tumor targeting by down-regulating DNAM-1 on NK cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 8, pp. 4921-30, (2009) (PubMed).

    Kindberg, Ax, Fiore, Svensson: "Ala67Thr mutation in the poliovirus receptor CD155 is a potential risk factor for vaccine and wild-type paralytic poliomyelitis." in: Journal of medical virology, Vol. 81, Issue 5, pp. 933-6, (2009) (PubMed).

  • Target
    Poliovirus Receptor (PVR)
    Andere Bezeichnung
    PVR (PVR Produkte)
    Synonyme
    PVR antikoerper, CD155 antikoerper, HVED antikoerper, NECL5 antikoerper, Necl-5 antikoerper, PVS antikoerper, TAGE4 antikoerper, 3830421F03Rik antikoerper, D7Ertd458e antikoerper, Taa1 antikoerper, Tage4 antikoerper, mE4 antikoerper, necl-5 antikoerper, poliovirus receptor antikoerper, PVR antikoerper, Pvr antikoerper
    Hintergrund
    The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
    Molekulargewicht
    45303
    NCBI Accession
    NP_001129240, NP_001129241, NP_001129242, NP_006496
    UniProt
    P15151
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interaktom
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