PLCD1 Antikörper (AA 14-549) (HRP)

Produktnummer ABIN8022164

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PLCD1 in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für PLCD1 Antikörper (AA 14-549) (HRP) (ABIN8022164)

Target: PLCD1 (phospholipase C, delta 1 (PLCD1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLCD1 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-PLCD1 Antikörper (HRP)

Bindungsspezifität: AA 14-549

Verwendungszweck: Anti-PLCD1 Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human PLCD1 shares 92.2%,92.5% amino acid (aa) sequence identity with mouse,rat PLCD1,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PLCD1 recombinant protein (Position: Q14-R549). Human PLCD1 shares 92.2% and 92.5% amino acid (aa) sequence identity with mouse and rat PLCD1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PLCD1

Target: PLCD1 (phospholipase C, delta 1 (PLCD1))

Andere Bezeichnung: PLCD1

Hintergrund:

Background: This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: phospholipase C delta 1

Gen-ID: 5333

UniProt: P51178

Pathways: WNT Signalweg, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process