PIK3R5 Antikörper (AA 170-864) (Cy3)

Produktnummer ABIN8021913

Der Kaninchen Polyklonal anti-PIK3R5 Antikörper wird verwendet zum Nachweis von PIK3R5 in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für PIK3R5 Antikörper (AA 170-864) (Cy3) (ABIN8021913)

Target: PIK3R5 (Phosphoinositide-3-Kinase, Regulatory Subunit 5 (PIK3R5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIK3R5 Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-PIK3R5 Antikörper (Cy3)

Bindungsspezifität: AA 170-864

Verwendungszweck: Anti-PIK3R5 Antibody Cy3 Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Human PIK3R5 shares 83.9% amino acid (aa) sequence identity with mouse PIK3R5.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PIK3R5 recombinant protein (Position: E170-L864). Human PIK3R5 shares 83.9% amino acid (aa) sequence identity with mouse PIK3R5.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu PIK3R5

Target: PIK3R5 (Phosphoinositide-3-Kinase, Regulatory Subunit 5 (PIK3R5))

Andere Bezeichnung: PIK3R5

Hintergrund:

Background: Phosphoinositide 3-kinase regulatory subunit 5 is an enzyme that in humans is encoded by the PIK3R5 gene. Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found.

Gene Full Name: phosphoinositide-3-kinase regulatory subunit 5

Gen-ID: 23533

UniProt: Q8WYR1

Pathways: PI3K-Akt Signalweg, Inositol Metabolic Process, Hepatitis C, VEGF Signaling