PTF1A Antikörper (AA 1-292) (HRP)

Produktnummer ABIN8019323

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PTF1A in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für PTF1A Antikörper (AA 1-292) (HRP) (ABIN8019323)

Target: PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTF1A Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-PTF1A Antikörper (HRP)

Bindungsspezifität: AA 1-292

Verwendungszweck: Anti-PTF1A Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PTF1A recombinant protein (Position: M1-Q292).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PTF1A

Target: PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))

Andere Bezeichnung: PTF1A

Hintergrund:

Background: Pancreas transcription factor 1 subunit alpha is a protein that in humans is encoded by the PTF1A gene. It is mapped to 10p12.2. This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers.

Gene Full Name: pancreas associated transcription factor 1a

Gen-ID: 256297

UniProt: Q7RTS3

Pathways: Retinoic Acid Receptor Signaling Pathway