NLRP7 Antikörper (AA 1-169) (HRP)

Produktnummer ABIN8015929

Der HRP-konjugierte Kaninchen Polyklonal anti-NLRP7 Antikörper (ABIN8015929) detektiert spezifisch NLRP7 in ELISA, IHC und WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für NLRP7 Antikörper (AA 1-169) (HRP) (ABIN8015929)

Target: NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP7 Antikörper ist konjugiert mit HRP

Applikation: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Produktdetails anti-NLRP7 Antikörper (HRP)

Bindungsspezifität: AA 1-169

Verwendungszweck: Anti-NLRP7 Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human NLRP7 recombinant protein (Position: M1-L169).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu NLRP7

Target: NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))

Andere Bezeichnung: NLRP7

Hintergrund:

Background: NACHT, LRR and PYD domains-containing protein 7 is a protein that in humans is encoded by the NLRP7 gene. This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: NLR family pyrin domain containing 7

Gen-ID: 199713

UniProt: Q8WX94

Pathways: Inflammasome