NLRP6 Antikörper (AA 14-887)

Produktnummer ABIN8015922

Der Kaninchen Polyklonal anti-NLRP6 Antikörper wird verwendet zum Nachweis von NLRP6 in Proben von Human. Er wurde validiert für ELISA, WB und FACS.

Kurzübersicht für NLRP6 Antikörper (AA 14-887) (ABIN8015922)

Target: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP6 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Güteklasse: Carrier-free

Produktdetails anti-NLRP6 Antikörper

Bindungsspezifität: AA 14-887

Verwendungszweck: Anti-NLRP6 Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human NLRP6 shares 71.7%,72.9% amino acid (aa) sequence identity with mouse,rat NLRP6,respectively.

Produktmerkmale: Anti-NLRP6 Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human NLRP6 recombinant protein (Position: R14-E887). Human NLRP6 shares 71.7% and 72.9% amino acid (aa) sequence identity with mouse and rat NLRP6, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu NLRP6

Target: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Andere Bezeichnung: NLRP6

Hintergrund:

Background: The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: NLR family pyrin domain containing 6

Molekulargewicht: 105 kDa

Gen-ID: 171389

UniProt: P59044

Pathways: Inflammasome