Neurexin 1 Antikörper (AA 141-294) (Fluoro594)

Produktnummer ABIN8014563

Der Kaninchen Polyklonal anti-Neurexin 1 Antikörper wird verwendet zum Nachweis von Neurexin 1 in Proben von Human. Er wurde validiert für FACS.

Kurzübersicht für Neurexin 1 Antikörper (AA 141-294) (Fluoro594) (ABIN8014563)

Target: Neurexin 1 (NRXN1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neurexin 1 Antikörper ist konjugiert mit Fluoro594

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Neurexin 1 Antikörper (Fluoro594)

Bindungsspezifität: AA 141-294

Verwendungszweck: Anti-Neurexin 1/NRXN1 Antibody Fluoro594 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human Neurexin 1 recombinant protein (Position: D141-E294).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Neurexin 1

Target: Neurexin 1 (NRXN1)

Andere Bezeichnung: NRXN1

Hintergrund:

Background: Neurexin-1-alpha is a protein that in humans is encoded by the NRXN1 gene. This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca (2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3,000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia.

Gene Full Name: neurexin 1

Gen-ID: 9378

UniProt: P58400

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development