MYBL1 Antikörper (AA 199-752) (HRP)

Produktnummer ABIN8012264

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MYBL1 in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für MYBL1 Antikörper (AA 199-752) (HRP) (ABIN8012264)

Target: MYBL1 (Myb-Like Protein 1 (MYBL1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYBL1 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-MYBL1 Antikörper (HRP)

Bindungsspezifität: AA 199-752

Verwendungszweck: Anti-v-Myb/MYBL1 Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human v-Myb/MYBL1 recombinant protein (Position: K199-L752).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu MYBL1

Target: MYBL1 (Myb-Like Protein 1 (MYBL1))

Andere Bezeichnung: MYBL1

Hintergrund:

Background: MYB proto-oncogene like 1 is a protein that in humans is encoded by the MYBL1 gene. A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes. Both A-Myb and B-Myb are expressed in t (14:18) lymphoma cells where they then inhibit cell arrest and apoptotic signaling. Expression of B-Myb rescues cells from p53-induced G1 phase arrest that is mediated by p21, while A-Myb functions as an anti-apoptotic factor by effectively activating the bcl-2 promoter and thereby up-regulating Bcl-2 expression.

Gene Full Name: MYB proto-oncogene like 1

Gen-ID: 4603

UniProt: P10243

Pathways: Zellzyklus, Chromatin Binding