MUTYH Antikörper (AA 1-559) (APC)
Kurzübersicht für MUTYH Antikörper (AA 1-559) (APC) (ABIN8012232)
Target
Alle MUTYH Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-559
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Verwendungszweck
- Anti-MUTYH Antibody APC Conjugated
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Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
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Homologie
- Human IFFO1 shares 94.1% amino acid (aa) sequence identity with mouse IFFO1.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human IFFO1 recombinant protein (Position: M1-R559). Human IFFO1 shares 94.1% amino acid (aa) sequence identity with mouse IFFO1.
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Isotyp
- IgG
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Applikationshinweise
- Flow Cytometry, Optimal dilutions should be determined by end users.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Haltbarkeit
- 12 months
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- MUTYH (MutY Homolog (E. Coli) (MUTYH))
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Andere Bezeichnung
- MUTYH
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Hintergrund
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Background: This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. This gene product is thought to play a role in signaling apoptosis by the introduction of single-strand breaks following oxidative damage. Mutations in this gene result in heritable predisposition to colorectal cancer, termed MUTYH-associated polyposis (MAP). Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: mutY DNA glycosylase
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Gen-ID
- 4595
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UniProt
- Q9UIF7
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Pathways
- DNA Reparatur
Target
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