MSH2 Antikörper (AA 337-934) (Fluoro488)
Kurzübersicht für MSH2 Antikörper (AA 337-934) (Fluoro488) (ABIN8010588)
Target
Alle MSH2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 337-934
-
Verwendungszweck
- Anti-MSH2 Antibody Fluoro488 Conjugated
-
Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
-
Aufreinigung
- Immunogen affinity purified.
-
Immunogen
- E.coli-derived human MSH2 recombinant protein (Position: Q337-T934).
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
Haltbarkeit
- 12 months
-
-
- MSH2 (Mismatch Repair Protein 2 (MSH2))
-
Andere Bezeichnung
- MSH2
-
Hintergrund
-
Background: DNA mismatch repair protein Msh2, also known as MutS protein homolog 2 or MSH2, is a protein that in humans is encoded by the MSH2 gene, which is located on chromosome 2. MSH2 is a tumor suppressor gene and more specifically a caretaker gene that codes for a DNA mismatch repair (MMR) protein, MSH2 which forms aheterodimer with MSH6 to make the human MutSα mismatch repair complex. It also dimerizes with MSH3 to form the MutSβ DNA repair complex. MSH2 is involved in many different forms of DNA repair, including transcription-coupled repair, homologous recombination, and base excision repair. It has been found that MSH2 may also be a coactivator of ESR1-dependent gene expression.
Gene Full Name: mutS homolog 2
-
Gen-ID
- 4436
-
UniProt
- P43246
-
Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
Target
-