MBD4 Antikörper (AA 238-534) (APC)

Produktnummer ABIN8009613

Der Kaninchen Polyklonal anti-MBD4 Antikörper wird verwendet zum Nachweis von MBD4 in Proben von Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für MBD4 Antikörper (AA 238-534) (APC) (ABIN8009613)

Target: MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MBD4 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-MBD4 Antikörper (APC)

Bindungsspezifität: AA 238-534

Verwendungszweck: Anti-Mbd4 Antibody APC Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Mouse Mbd4 shares 69.7% amino acid (aa) sequence identity with human MBD4.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Mbd4 recombinant protein (Position: R238-D534). Mouse Mbd4 shares 69.7% amino acid (aa) sequence identity with human MBD4.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu MBD4

Target: MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))

Andere Bezeichnung: Mbd4

Hintergrund:

Background: Methyl-CpG-binding domain protein 4 is a protein that in humans is encoded by the MBD4 gene. It is mapped to 3q21.3. The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: methyl-CpG binding domain protein 4

Gen-ID: 17193

UniProt: Q9Z2D7

Pathways: DNA Reparatur