MAEL Antikörper (AA 73-347) (Cy3)

Produktnummer ABIN8007341

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MAEL in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für MAEL Antikörper (AA 73-347) (Cy3) (ABIN8007341)

Target: MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAEL Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-MAEL Antikörper (Cy3)

Bindungsspezifität: AA 73-347

Verwendungszweck: Anti-MAEL Antibody Cy3 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human MAEL recombinant protein (Position: E73-Q347).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu MAEL

Target: MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

Andere Bezeichnung: MAEL

Hintergrund:

Background: The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.

Gene Full Name: maelstrom spermatogenic transposon silencer

Gen-ID: 84944

UniProt: Q96JY0