MAEL Antikörper (AA 73-347) (HRP)

Produktnummer ABIN8007346

Der HRP-konjugierte Kaninchen Polyklonal anti-MAEL Antikörper (ABIN8007346) detektiert spezifisch MAEL in ELISA, WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für MAEL Antikörper (AA 73-347) (HRP) (ABIN8007346)

Target: MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAEL Antikörper ist konjugiert mit HRP

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-MAEL Antikörper (HRP)

Bindungsspezifität: AA 73-347

Verwendungszweck: Anti-MAEL Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human MAEL recombinant protein (Position: E73-Q347).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu MAEL

Target: MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

Andere Bezeichnung: MAEL

Hintergrund:

Background: The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.

Gene Full Name: maelstrom spermatogenic transposon silencer

Gen-ID: 84944

UniProt: Q96JY0