MAEL Antikörper (AA 73-347)

Produktnummer ABIN7876680

Der Kaninchen Polyklonal anti-MAEL Antikörper wird verwendet zum Nachweis von MAEL in Proben von Human. Er wurde validiert für ELISA, WB und FACS.

Kurzübersicht für MAEL Antikörper (AA 73-347) (ABIN7876680)

Target: MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAEL Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-MAEL Antikörper

Bindungsspezifität: AA 73-347

Verwendungszweck: MAEL Antibody / Maelstrom homolog

Aufreinigung: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (E73-Q347) was used as the immunogen for the MAEL antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the MAEL antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the MAEL antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu MAEL

Target: MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

Andere Bezeichnung: MAEL

Hintergrund: The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.

UniProt: Q96JY0