Lamin B2 Antikörper (AA 128-585) (Biotin)

Produktnummer ABIN8005028

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Lamin B2 in WB, IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für Lamin B2 Antikörper (AA 128-585) (Biotin) (ABIN8005028)

Target: Lamin B2 (LMNB2)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Lamin B2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-Lamin B2 Antikörper (Biotin)

Bindungsspezifität: AA 128-585

Verwendungszweck: Anti-Lamin B2/LMNB2 Antibody Biotin Conjugated

Homologie: Human LMNB2 shares 81.8% amino acid (aa) sequence identity with mouse LMNB2.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Lamin B2/LMNB2 recombinant protein (Position: L128-E585). Human LMNB2 shares 81.8% amino acid (aa) sequence identity with mouse LMNB2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Lamin B2

Target: Lamin B2 (LMNB2)

Andere Bezeichnung: Lamin B2/LMNB2

Hintergrund:

Background: Lamin B2 is a protein that in humans is encoded by the LMNB2 gene. This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy.

Gene Full Name: lamin B2

Gen-ID: 84823

UniProt: Q03252

Pathways: Apoptose, Caspase Kaskade in der Apoptose