KIF7 Antikörper (Middle Region) (Fluoro647)

Produktnummer ABIN8004519

Der Kaninchen Polyklonal anti-KIF7 Antikörper wird verwendet zum Nachweis von KIF7 in Proben von Human. Er wurde validiert für FACS.

Kurzübersicht für KIF7 Antikörper (Middle Region) (Fluoro647) (ABIN8004519)

Target: KIF7 (Kinesin Family Member 7 (KIF7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIF7 Antikörper ist konjugiert mit Fluoro647

Applikation: Flow Cytometry (FACS)

Produktdetails anti-KIF7 Antikörper (Fluoro647)

Bindungsspezifität: Middle Region

Verwendungszweck: Anti-KIF7 Antibody Fluoro647 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: identical to the related mouse sequences.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human KIF7, identical to the related mouse sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu KIF7

Target: KIF7 (Kinesin Family Member 7 (KIF7))

Andere Bezeichnung: KIF7

Hintergrund:

Background: This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.

Gene Full Name: kinesin family member 7

Gen-ID: 374654

UniProt: Q2M1P5

Pathways: Hedgehog Signalweg