KIF7 Antikörper (Middle Region) (Fluoro488)

Produktnummer ABIN8004512

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch KIF7 in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für KIF7 Antikörper (Middle Region) (Fluoro488) (ABIN8004512)

Target: KIF7 (Kinesin Family Member 7 (KIF7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIF7 Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-KIF7 Antikörper (Fluoro488)

Bindungsspezifität: Middle Region

Verwendungszweck: Anti-KIF7 Antibody Fluoro488 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: identical to the related mouse sequences.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human KIF7, identical to the related mouse sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu KIF7

Target: KIF7 (Kinesin Family Member 7 (KIF7))

Andere Bezeichnung: KIF7

Hintergrund:

Background: This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.

Gene Full Name: kinesin family member 7

Gen-ID: 374654

UniProt: Q2M1P5

Pathways: Hedgehog Signalweg