IRF3 Antikörper (AA 1-427) (Cy3)
Kurzübersicht für IRF3 Antikörper (AA 1-427) (Cy3) (ABIN8001210)
Target
Alle IRF3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 1-427
-
Verwendungszweck
- Anti-IRF3 Antibody Cy3 Conjugated
-
Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
-
Aufreinigung
- Immunogen affinity purified.
-
Immunogen
- E.coli-derived human IRF3 recombinant protein (Position: M1-S427).
-
Isotyp
- IgG
-
-
anti-Interferon Regulatory Factor 3 (IRF3) (pSer396) antibody
IRF3 Reaktivität: Human, Maus, Ratte, Affe WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-260) antibodyIRF3 Reaktivität: Human WB, IHC, IF, ChIP Wirt: Kaninchen Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-452) antibodyIRF3 Reaktivität: Human WB, ELISA, IF, IP Wirt: Maus Monoclonal 3C8 unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-360) antibodyIRF3 Reaktivität: Human WB, IHC, FACS, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (pSer386) antibodyIRF3 Reaktivität: Human, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (C-Term) antibodyIRF3 Reaktivität: Human WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 51-150) antibodyIRF3 Reaktivität: Human, Maus, Ratte, Affe, Rind (Kuh) WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 5-422) antibodyIRF3 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) antibodyIRF3 Reaktivität: Human, Maus, Ratte WB, IHC (p), IF (cc) Wirt: Kaninchen Monoclonal 4C3 unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-427) antibodyIRF3 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
-
-
Applikationshinweise
- Flow Cytometry, 1-3 μg/1x106 cells
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
Haltbarkeit
- 12 months
-
-
- IRF3 (Interferon Regulatory Factor 3 (IRF3))
-
Andere Bezeichnung
- IRF3
-
Hintergrund
-
Background: IRF3 (interferon regulatory factor 3)is a member of the interferon regulatory transcription factor (IRF) family. The IRF3 gene is mapped on 19q13.33. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex withCREBBP. IRF3 plays an important role in theinnate immune system's response toviral infection. AggregatedMAVShave been found to activate IRF3 dimerization. AlthoughIRF3increased transcriptional activity from an ISRE-containing promoter, expression ofIRF3as a Gal4 fusion protein did not activate expression of a chloramphenicol acetyltransferase (CAT) < a href=https://www.bosterbio.com/cells/reporter-cell-lines style=color:#ea8d28>reporter gene containing repeats of the Gal4-binding sites.Translocation of IRF3 was accompanied by an increase in serine and threonine phosphorylation.The transcriptional activators CREBBP and EP300 coimmunoprecipitated withIRF3only subsequent to viral infection, and the authors stated that these are also subunits of DRAF1.
Gene Full Name: interferon regulatory factor 3
-
Gen-ID
- 3661
-
UniProt
- Q14653
-
Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
Target
-
