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Insulin Receptor Antikörper (AA 168-621) (FITC)

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Insulin Receptor in FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.
Produktnummer ABIN7999850
720,50 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 8 bis 12 Werktagen

Kurzübersicht für Insulin Receptor Antikörper (AA 168-621) (FITC) (ABIN7999850)

Target

Alle Insulin Receptor (INSR) Antikörper anzeigen
Insulin Receptor (INSR)

Reaktivität

  • 242
  • 135
  • 132
  • 14
  • 13
  • 8
  • 7
  • 6
  • 6
  • 6
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 211
  • 44
  • 6
  • 2
Kaninchen

Klonalität

  • 177
  • 86
Polyklonal

Konjugat

  • 140
  • 19
  • 19
  • 10
  • 9
  • 8
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Insulin Receptor Antikörper ist konjugiert mit FITC

Applikation

  • 168
  • 84
  • 82
  • 45
  • 34
  • 32
  • 28
  • 14
  • 13
  • 13
  • 9
  • 5
  • 5
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • Bindungsspezifität

    • 23
    • 22
    • 16
    • 13
    • 11
    • 8
    • 8
    • 8
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 168-621

    Verwendungszweck

    Anti-Insulin Receptor/INSR Antibody FITC Conjugated

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human Insulin Receptor/INSR recombinant protein (Position: E168-N621).

    Isotyp

    IgG
  • Applikationshinweise

    Flow Cytometry, Optimal dilutions should be determined by end users.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    Haltbarkeit

    12 months
  • Target

    Insulin Receptor (INSR)

    Andere Bezeichnung

    INSR

    Hintergrund

    Background: INSR(INSULIN RECEPTOR) is a tetramer of 2 alpha and 2 beta subunits that are coded by a single gene and are joined by disulfide bonds, a mechanism parallel to that of its ligand, insulin. It belongs to the large class of tyrosine kinase receptors. The insulin receptor gene is mapped to 19p13.2. The insulin receptor mediates their activity by causing the addition of a phosphate group to particular tyrosines on certain proteins within a cell. The INSR gene spans more than 120 kb and has 22 exons. Functional studies of the INSR SNPs show no effect on mRNA levels or splicing in peripheral blood leukocytes or on binding of insulin to mononuclear cells.

    Gene Full Name: insulin receptor

    Gen-ID

    3643

    UniProt

    P06213

    Pathways

    NF-kappaB Signalweg, RTK Signalweg, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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