Insulin Receptor Antikörper (AA 168-621) (Fluoro488)
Kurzübersicht für Insulin Receptor Antikörper (AA 168-621) (Fluoro488) (ABIN7999847)
Target
Alle Insulin Receptor (INSR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 168-621
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Verwendungszweck
- Anti-Insulin Receptor/INSR Antibody Fluoro488 Conjugated
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human Insulin Receptor/INSR recombinant protein (Position: E168-N621).
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Isotyp
- IgG
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anti-Insulin Receptor (INSR) antibody
INSR Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal C7 unconjugated
anti-Insulin Receptor (INSR) (AA 1024-1298) antibodyINSR Reaktivität: Human WB, IHC, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 1101-1372) antibodyINSR Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 1027-1364) antibodyINSR Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Receptor (INSR) (C-Term) antibodyINSR Reaktivität: Human, Maus, Ratte, Affe, Hund, Pferd, Schwein, Rind (Kuh), Meerschweinchen, Kaninchen, Schaf, Hamster, Huhn, Avian, Cat, Esel, Ziege WB, IHC (p), IHC (fro) Wirt: Ziege Polyclonal unconjugated
anti-Insulin Receptor (INSR) (C-Term) antibodyKO Validated INSR Reaktivität: Human WB, ICC, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 1325-1358) antibodyINSR Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB50340 unconjugated
anti-Insulin Receptor (INSR) (AA 51-150) antibodyINSR Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 1023-1298) antibodyINSR Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Receptor (INSR) antibodyKD Validated INSR Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 23GB2050 unconjugated Recombinant Antibody
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Applikationshinweise
- Flow Cytometry, Optimal dilutions should be determined by end users.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Haltbarkeit
- 12 months
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- Insulin Receptor (INSR)
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Andere Bezeichnung
- INSR
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Hintergrund
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Background: INSR(INSULIN RECEPTOR) is a tetramer of 2 alpha and 2 beta subunits that are coded by a single gene and are joined by disulfide bonds, a mechanism parallel to that of its ligand, insulin. It belongs to the large class of tyrosine kinase receptors. The insulin receptor gene is mapped to 19p13.2. The insulin receptor mediates their activity by causing the addition of a phosphate group to particular tyrosines on certain proteins within a cell. The INSR gene spans more than 120 kb and has 22 exons. Functional studies of the INSR SNPs show no effect on mRNA levels or splicing in peripheral blood leukocytes or on binding of insulin to mononuclear cells.
Gene Full Name: insulin receptor
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Gen-ID
- 3643
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UniProt
- P06213
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Pathways
- NF-kappaB Signalweg, RTK Signalweg, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
Target
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