IRGM Antikörper (AA 50-333) (Biotin)

Produktnummer ABIN7999159

Der Kaninchen Polyklonal anti-IRGM Antikörper wird verwendet zum Nachweis von IRGM in Proben von Maus. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für IRGM Antikörper (AA 50-333) (Biotin) (ABIN7999159)

Target: IRGM (Immunity-Related GTPase Family, M (IRGM))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRGM Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-IRGM Antikörper (Biotin)

Bindungsspezifität: AA 50-333

Verwendungszweck: Anti-IRGM/Irgm1 Antibody Biotin Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse IRGM/Irgm1 recombinant protein (Position: E50-K333).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu IRGM

Target: IRGM (Immunity-Related GTPase Family, M (IRGM))

Andere Bezeichnung: Irgm1

Hintergrund:

Background: Immunity-related GTPase family M protein (IRGM), also known as interferon-inducible protein 1 (IFI1), is an enzyme that in humans is IRGM gene. This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: immunity-related GTPase family M member 1

Gen-ID: 15944

UniProt: Q60766