IRGM Antikörper (AA 101-150)

Produktnummer ABIN7229186

Der Kaninchen Polyklonal anti-IRGM Antikörper wird verwendet zum Nachweis von IRGM in Proben von Human und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für IRGM Antikörper (AA 101-150) (ABIN7229186)

Target: IRGM (Immunity-Related GTPase Family, M (IRGM))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRGM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-IRGM Antikörper

Bindungsspezifität: AA 101-150

Verwendungszweck: Rabbit Anti-IRGM Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of IRGM protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human IRGM protein at AA range: 101-150

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu IRGM

Target: IRGM (Immunity-Related GTPase Family, M (IRGM))

Andere Bezeichnung: IRGM

Hintergrund: Immunity-related GTPase family M protein, Immunity-related GTPase family M protein 1, Interferon-inducible protein 1, LPS-stimulated RAW 264.7 macrophage protein 47 homolog, LRG-47IRGM encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of IRGM are associated with a susceptibility to Crohn's disease and tuberculosis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 19kD

Gen-ID: 345611

UniProt: A1A4Y4