HYAL1 Antikörper (C-Term) (FITC)

Produktnummer ABIN7998537

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HYAL1 in FACS. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für HYAL1 Antikörper (C-Term) (FITC) (ABIN7998537)

Target: HYAL1 (Hyaluronidase-1 (HYAL1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HYAL1 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-HYAL1 Antikörper (FITC)

Bindungsspezifität: C-Term

Verwendungszweck: Anti-Hyaluronidase-1 HYAL1 Antibody FITC Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: different from the related rat sequence by one amino acid.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse HYAL1, different from the related rat sequence by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu HYAL1

Target: HYAL1 (Hyaluronidase-1 (HYAL1))

Andere Bezeichnung: HYAL1

Hintergrund:

Background: Hyaluronidase-1, also known as HYAL1 or LUCA1, is an enzyme that in humans is encoded by the HYAL1 gene. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is though to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency.

Gene Full Name: hyaluronoglucosaminidase 1

Sequence Similarities: Belongs to the glycosyl hydrolase 56 family.

Gen-ID: 15586

UniProt: Q91ZJ9

Pathways: Glycosaminoglycan Metabolic Process