CSF1R Antikörper (AA 201-300) (Cy5)

Produktnummer ABIN750147

Dieses Anti-CSF1R-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CSF1R in FACS, IF (p) und IF (cc). Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für CSF1R Antikörper (AA 201-300) (Cy5) (ABIN750147)

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CSF1R Antikörper ist konjugiert mit Cy5

Applikation: Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Produktdetails anti-CSF1R Antikörper (Cy5)

Bindungsspezifität: AA 201-300

Kreuzreaktivität: Human

Homologie: Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MCSF receptor

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CSF1R Antikörper (Cy5) (ABIN750147)

Gorden, Saha, Khammanivong, Schwartz, Dickerson: "Lysosomal drug sequestration as a mechanism of drug resistance in vascular sarcoma cells marked by high CSF-1R expression." in: Vascular cell, Vol. 6, pp. 20, (2014) (PubMed).

Details zu CSF1R

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Andere Bezeichnung: MCSF Receptor

Hintergrund:

Synonyms: FMS, CSFR, FIM2, HDLS, C-FMS, CD115, CSF-1R, M-CSF-R, Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor, CSF-1-R, Proto-oncogene c-Fms, CSF1R, CSF1R_HUMAN

Background: The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Gen-ID: 1436

UniProt: P07333

Pathways: RTK Signalweg, Inositol Metabolic Process, Cell-Cell Junction Organization