Hexokinase 1 Antikörper (AA 17-323) (HRP)

Produktnummer ABIN7997426

Der HRP-konjugierte Maus Monoklonal anti-Hexokinase 1 Antikörper (Klon 4B7) (ABIN7997426) detektiert spezifisch Hexokinase 1 in WB, IHC und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Hexokinase 1 Antikörper (AA 17-323) (HRP) (ABIN7997426)

Target: Hexokinase 1 (HK1)

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Hexokinase 1 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon: 4B7

Produktdetails anti-Hexokinase 1 Antikörper (HRP)

Bindungsspezifität: AA 17-323

Verwendungszweck: Anti-Hexokinase 1/HK1 Antibody (monoclonal, 4B7) HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Hexokinase 1/HK1 recombinant protein (Position: D17-R323).

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Hexokinase 1

Target: Hexokinase 1 (HK1)

Andere Bezeichnung: HK1

Hintergrund:

Background: Hexokinase-1 (HK1) is an enzyme that in humans is encoded by the HK1 gene on chromosome 10. It is mapped to 10q22.1. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.

Gene Full Name: hexokinase 1

Gen-ID: 3098

UniProt: P19367

Pathways: Carbohydrate Homeostasis, Warburg Effekt