TP53BP1 Antikörper (AA 501-600)

Produktnummer ABIN749933

Der Kaninchen Polyklonal Anti-TP53BP1-Antikörper wurde für ELISA, ICC, IF (cc), IF (p), IHC (p) und IHC (fro) validiert. Er ist geeignet, TP53BP1 in Proben von Ratte zu detektieren.

Kurzübersicht für TP53BP1 Antikörper (AA 501-600) (ABIN749933)

Target: TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TP53BP1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-TP53BP1 Antikörper

Bindungsspezifität: AA 501-600

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human p53BP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu TP53BP1

Target: TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Andere Bezeichnung: p53BP1

Hintergrund:

Synonyms: 53 BP1, FLJ41424, MGC138366, p202, p53 binding protein 1, p53 BP1, p53BP1, TP53 BP1, TP53BP1, Tumor protein 53 binding protein 1, Tumor protein p53 binding protein 1, Tumor suppressor p53 binding protein 1, TP53B_HUMAN, tumor protein 53-binding protein, 1.

Background: p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.

Gen-ID: 7158

Pathways: DNA Reparatur