GRB10 Antikörper (AA 1-251) (Biotin)

Produktnummer ABIN7995372

Dieser Maus Monoklonal Antikörper detektiert spezifisch GRB10 in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Affe.

Kurzübersicht für GRB10 Antikörper (AA 1-251) (Biotin) (ABIN7995372)

Target: GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))

Reaktivität: Human, Ratte, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GRB10 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Klon: 5H7

Produktdetails anti-GRB10 Antikörper (Biotin)

Bindungsspezifität: AA 1-251

Verwendungszweck: Anti-GRB10 Antibody (monoclonal, 5H7) Biotin Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human GRB10 recombinant protein (Position: M1-K251).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu GRB10

Target: GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))

Andere Bezeichnung: GRB10

Hintergrund:

Background: GRB10, Growth factor receptor-bound protein 10, also known as insulin receptor-binding protein Grb-IR is a protein that in humans is encoded by the GRB10 gene. The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors (e.g., IGF1R and IGF2R). Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Full Name: growth factor receptor bound protein 10

Gen-ID: 2887

UniProt: Q13322

Pathways: Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2